Topical remedy



UNITED STATES PATENT OFFICE.

\VITLTAM ll. LA ROSAE AND RALPH \V. iUZARD, OF BROOKVILLE, INDIANA.

TOPICAL REMEDY.

SPECIFICATION forming part of Letters Patent No. 417,254, dated. December 17, 1889.

Application filed March 21, 1889. Serial No. 30 L202. (No specimens.)

To aZZ whom it may concern.-

Be it known that we, TILLIAM H. LA ROSAE and RALPH \V. BUZARD, citizens of the United States, residing at Brookville, in the county of Franklin and State of Indiana, have invented a new and useful Anaesthetic Compound, of which the following is a specification.

The invention relates to an anaesthetic compound designed to be used in dental and other surgical operations; and it consists of the following ingredients in the proportions named: crystals of menthol, eight parts; tincture of cannabis indica, sixteen parts; tincture of gelsemium, two parts; tincture of veratrum viride, two parts; chloroform, one part; oil of sassafras, one part; sulphuric ether, one part; deodorizcd alcohol, sixtythree parts.

Place the alcohol in a suitable vessel, and after adding the menthol agitate until the latter is thoroughly dissolved. After standing for about ten minutes add the cannabis indica, gelsemium, and veratrum viride separately, thoroughly mixing each with the solution of cannabis indica before adding the next. After agitating vigorously for about fifteen minutes add the sulphuric ether and chloroform, and allow the mixture to stand for one half hour. Then add the oil of sassafras and agitate slowly for fifteen minutes.

The menthol and cannabis indica are an aesthetics, serving to deaden the nerves and deprive them of feeling. The gclsemiuin an d veratrum viride produce together a rigidity of the tissues and ligaments, the former serving to moderate the effect of the latter, as the latter alone would have too great an effect. The chloroform and sulphuric other are used in this compound as febrifuges to prevent the fever which is liable to result is used to give the compound a pleasant flavor.

The compound may be applied to the surface by means of a sponge, or it may be injected by means of a hypodermic syringe, according to the requirements of the case. The effect of the anaesthetic continues from twenty to thirty minutes.

The advantages of the compound are that no lasting effect is produced upon the patients, no unpleasant flavor is left in the mouth, and it may be applied to persons of all ages and temperaments without produc ing deleterious effects.

The'compound herein described is designed merely as a local application, but may be used in some cases with great advantage as a hypodermic injection. It is adapted for use in surgical operations, more especially in dental operations, and the manner of using depends greatly upon the character of the case; but in ordinary cases may be briefly described as follows: Place upon a small sponge about five drops of the medicine and apply to the gums in the immediate locality of the teeth or to whatever portion of the body to be subjected to a subsequent operation. Hold the sponge in its place during a period of about two minutes, then remove, an d, if desired, inject with a hypodermic needle. The dose of injections varies from three to eight drops, the maximum onlybeing used when the dentine is extremely sensitive. In cleaning and filling teeth the hypodermic inj ection is not necessary unless the gums are very sore. The local application may be repeated as often as is found necessary in order that the gums may be n'iaintained in an insensitive state.

hen the medicine is applied to other mucous tissues, the dose in local application is from six to ten drops, and in hypodermic inj ections from six to twelve drops.

A surgeon aft-er having familiarized himself with the results of the medicine, however, may regulate the dose in accordance with his experience and experiments and to In testimony that we claim the foregoing as [0 meet the requirements of his special case. our own we have hereto affixed our signa- XVe c1aim tures in presence of two witnesses. The compound for the purpose named, con- TH LIAM H I A ROSAF sisting of menthol, tlnotures of cannabis LRALPH T. BUZARD.

indica, gelsemium, and veratrum Viride, chloroform, sulphuric ether, oil of sassafms, and \Vitnesses:

alcohol, in substantially the proportions speci- JrEORGE FRIES,

fied. SAMUEL S. ITARRELL. 

